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The search and rescue operation continues after a massive fertilizer plant explosion in West, Texas. Crews are going through the wreckage of some 75 homes and other buildings. Officials are not giving a death toll — though they are repeating the estimate between five and fifteen. More than 160 people were injured.

Robert Siegel talks to Robert McFadden, senior vice president of The Soufan Group and a 30-year veteran of federal law enforcement, about the latest news in the Boston Marathon bombing investigation.

Host Scott Simon speaks with Sarah Brady about current attempts to pass gun control legislation. Brady has been active in promoting additional gun control since her husband, former presidential press secretary James Brady, was shot in the head during the attempted assassination of President Ronald Reagan.

Humans have debated the concept of an afterlife for millennia. But ultimately, each individual's view on life after death is a personal one. For his part, the Rev. Gabriel Salguero, president of the National Latino Evangelical Coalition, sees eternity as a place where people cast aside the differences that divided them on earth.

The Senate immigration bill calls for tripling a controversial federal court program called Operation Streamline. The program takes people caught crossing the border illegally, gives them prison sentences, then deports them. It's hugely expensive — but does it work?

The school, simply named 42, requires no high school diploma and no money to apply. It's turning French education on its head, but it may also solve some of the country's most pressing problems.

A Metro-North train derailed this morning in the Bronx, killing four and injuring dozens of others. Arun Rath talks with NPR's Jim Zarroli about the crash and further developments.

The rollout of vaccines for COVID-19 has been slower than expected. Reasons include local logistics, lack of funding and staffing struggles during the winter holidays.

The Obama administration projected that within the first month of open enrollment for health insurance under the Affordable Care Act, half a million individuals or families would sign up. Nearly three weeks in, the actual number of enrollments looks to be much smaller. Technical issues have been a big factor.

Marissa Alexander, a Jacksonville woman behind bars for three years for firing a "warning shot" near her estranged husband, was recently released. NPR's Arun Rath talks with Larry Hannan of the Florida Times-Union.